Stem cells: the future of cosmetic medicine?

Our body’s natural regenerative capacity is partly thanks to our stem cells. Stem cells, often referred to as ‘baby cells,’ have the unique ability to mature into various cell types, such as nerve, bone, muscle, or skin cells. The specific location where a stem cell is placed determines the type of cell it will become. For instance, stem cells can generate new cartilage in a worn-out joint, restore disrupted skin structure in scars, rejuvenate sun-damaged skin, and even promote hair regrowth. The possibilities are endless.

How it works

The stem cells (ADSCs) extracted from your own body fat (such as the abdomen, flanks, or legs) have the ability to regenerate weakened skin, restore volume loss, or rejuvenate hair follicles. Stem cells, like ‘baby cells,’ can transform into various mature cell types, including those for skin, fat, bones, muscles, and cartilage. For facial treatment, an option is to reintroduce the stem cells along with the fat cells to not only enhance the skin but also restore youthful volume. In treatments focused on hair regrowth (or other areas where volume is not desired), the fat cells are filtered out, and only the fluid rich in growth factors and stem cells is injected.

How does a treatment look like?

In the subcutaneous fat, a significant number of stem cells are present. We can easily extract a small amount of this superficial fat tissue using a syringe under local anesthesia. Typically, the abdomen, flanks, or legs are commonly chosen for this procedure. The amount we remove is approximately equivalent to a shot of espresso (±30 ml.), so it’s not comparable to a typical liposuction. The area where the fat is ‘harvested’ may feel slightly tender for a few days after the procedure.

After harvesting the fat, the next step involves filtering the stem cells. This can be done in various ways depending on the desired effect. If we aim for both skin improvement and a volumizing effect in the face, we will reintroduce the fat cells and filter out the anesthetic solution. For treatments focused on restoring hair growth, we also filter out the fat cells using a centrifuge. This leaves behind a fluid rich in growth factors and stem cells.

Depending on the desired effect, the stem cells may or may not be re-implanted in combination with the fat cells. In a SEFFILLER treatment, we reintroduce the mix of stem cells and fat cells into the subcutaneous fat of the face using a small cannula. In a SEFFIHAIR treatment, we place the filtered stem cells (without fat cells) back into the scalp using a ‘multi-injector’ that allows us to administer multiple small injections simultaneously. The treatment is performed under local anesthesia using a numbing injection or cream.

In the first few days after the treatment, the skin needs some time to settle. Expect mild swelling, redness, and a slight tenderness. It’s possible to encounter a small blood vessel during the procedure, resulting in a bruise, especially in the area where the stem cells were harvested. Generally, the recovery is mild, and beautiful results are often visible quickly. Optimal results will become apparent once the stem cells have settled in, multiplied, and started replacing old damaged cells. This typically occurs within 3-6 months. Depending on your situation and the desired effect, the treatment may be performed in a course of 2 or 3 sessions for optimal results. The results can last for years.

The ‘Baselift’ is a treatment that combines the skin-tightening effect of Endolift (subcutaneous stimulation with radiofrequency) with the regenerative capability of stem cells. This allows us to target specific areas such as the lower eyelids with focused stimulation from Endolift, followed by the reinforcement of the recovery process through the regenerative effects of stem cells. The Endolift treatment can also be applied to facial support points to restore youthful contours in the face. If there is significant skin laxity, an operative ‘facelift’ might be a more suitable starting option. Afterward, you can maintain and optimize the skin condition with treatments based on the body’s natural regenerative capacity. Discuss with your doctor which option is most suitable for you.

We see a trend where people are increasingly seeking natural alternatives for a fresher appearance. Christopher J. Brandt - cosmetisch arts KNMG

SEFFILLER Amsterdam

SEFFILLER is a groundbreaking ‘fat transfer’ procedure that provides a younger and fuller appearance by harnessing the body’s natural regenerative ability of stem cells. The superficial subcutaneous fat contains significant quantities of ‘mesenchymal stem cells’ (ADSCs) and ‘stromal vascular fraction’ (SVF), in simpler terms: stem cells and growth factors that prompt your skin to regenerate cells, restore volume, stimulate collagen, elastin, new blood vessels, and more. The result: skin improvement and facial rejuvenation. In contrast to temporary fillers, the results can last for years.

stamcel behandeling amsterdam

 

 

SEFFIHAIR Amsterdam

Stop hair loss and stimulate new hair growth met SEFFIHAIR

Hair loss affects 70% of all men and 40% of all women, often having a significant impact on self-image. In men, the overproduction of the enzyme dihydrotestosterone (DHT) plays a crucial role in weakening hair follicles, leading to the typical male pattern baldness with a receding hairline and hair loss on the top of the head. In women, hormonal changes can contribute to hair loss, typically leaving the hairline intact but causing visible thinning of the hair.

stamcel haar behandeling

Frequently asked questions

SEFFILLER is a groundbreaking ‘fat transfer’ procedure that provides a younger and fuller appearance by harnessing the body’s natural regenerative ability of stem cells. The superficial subcutaneous fat contains significant quantities of ‘mesenchymal stem cells’ (ADSCs) and ‘stromal vascular fraction’ (SVF), in simpler terms: stem cells and growth factors that prompt your skin to regenerate cells, restore volume, stimulate collagen, elastin, new blood vessels, and more. The result: skin improvement and facial rejuvenation. Unlike temporary fillers, the results can last for years.

Hair loss affects 70% of all men and 40% of all women and can significantly impact self-esteem. In men, overproduction of the enzyme dihydrotestosterone (DHT) plays a crucial role in weakening hair follicles, leading to the typical male pattern baldness with a receding hairline (‘temples’) and hair loss on the top of the head. In women, hormonal changes can contribute to hair loss, typically leaving the hairline intact but causing visible thinning of the hair.

SEFFIHAIR is a medical treatment based on ‘autologous regenerative therapy’ (ART), where stem cells are extracted from the body’s own fat and re-implanted into the hairy scalp to stimulate new hair growth. This new technology has been proven safe, effective, and entirely natural.

The downtime is minimal and is limited to some local skin reactions at the injection sites (mild redness, swelling, and possibly a bruise for 24-72 hours). The area where the fat is ‘harvested’ may feel slightly tender for a few days. You can comfortably use makeup to conceal any post-treatment effects.

After a SEFFILLER treatment for the face, you’ll immediately notice a difference due to the volumizing effect of the transplanted fat cells. Around 8-12 weeks later, you’ll observe visible skin improvement; your skin becomes firmer and tighter. The complexion and skin hydration also improve. Optimal results are seen around 6 months, and these results can last for years.

In recent years, extensive scientific research has been conducted on treatments using the body’s own stem cells (ADSCs and SVF), demonstrating not only their high effectiveness but also the minimal risk of side effects. It’s an ‘autologous’ treatment, meaning your own tissue is used. In other words, nothing foreign enters your body. The treatment should be performed by a certified medical professional such as a ‘cosmetic physician KNMG,’ dermatologist, or plastic surgeon with proven experience in administering fillers or autologous fat ‘lipofilling.’

Depending on the condition of the skin or the extent of hair loss, it may be beneficial to repeat the treatment. Repeating the procedure can provide an additional ‘boost’ to the regenerative process, enhancing the visibility of even more beautiful results. It is recommended to repeat the treatment after 3 months. Discuss with your doctor how many sessions are necessary in your case to achieve the desired effect.

Seffiller

Better skin with stem cells

Volume restoration and skin improvement with growth factors and stem cells from your own body.

Dokter Brandt cosmetisch arts KNMG bij Blooming

New: 'Baselift'

Combine the skin-tightening effect of Endolift with the regenerative impact of stem cells.

Seffihair

Restore hair growth with stem cells.

Regenerative therapy for your hair with body’s own stem cells. Halts hair loss and stimulates new hair growth.

Costs of the treatment

It is possible to combine the treatment with the removal of wrinkles on other parts of the face. Check our price list for a complete overview.

In a SEFFILLER treatment, the middle and lower parts of the face (from the temples to the jawline) are treated with autologous fat cells and stem cells.

Individual treatment – €1950

Course of 2 treatments* – €3600

* Recommended. 2nd treatment after 3 months.

In a SEFFIHAIR treatment, the hairline and hairy scalp are treated with autologous stem cells and growth factors.

Individual treatment – €1850

Course of 2 treatments* – €3500

* Recommended. 2nd treatment after 3 months.

The ‘Baselift’ is the latest addition to the clinic’s range of treatments and is undoubtedly Dr. Brandt’s signature procedure. It’s a natural skin rejuvenation treatment without surgery or foreign substances.

 

Sagging skin around the eyes and cheeks:

Skin tightening with subcutaneous radiofrequency (INNOfill) + filtered stem cells (without fat cells) and growth factors (PRP) + microneedling – €2450

Course of 2 treatments* – €4550

*Recommended. 2nd treatment after 3 months.

 

Lifting treatments for cheeks and jawline:

Skin tightening with subcutaneous radiofrequency (INNOfill) + unfiltered stem cells (with fat cells) and growth factors (PRP) + microneedling – €2650

Course of 2 treatments* – €4950

* Recommended. 2nd treatment after 3 months.